Drug use among American workers is down by nearly 75 percent over the past 25 years, although the rate of positive test results for certain drugs, including amphetamine and opiates, continues to climb.

That finding is based on an analysis of workplace drug test results released this week by Quest Diagnostics, a testing company.

"The (1988) Drug-Free Workplace Act and the public and private initiatives it helped to spur have led to steep declines in drug use among much of the American workforce," said Laura Shelton, executive director, Drug and Alcohol Testing Industry Association. "While more needs to be done to reduce illicit drug use by workers, we should take heart from the tremendous progress employers have made to create safer workplaces for millions of Americans."

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